How To Choose a Good Scientific Problem

Are you struggling with trying to pick a dissertation topic? How do you know if the problem you have chosen to address is a "good problem"? What is a good scientific problem anyways? This article from Molecular Cell addresses these infrequently discussed topics, and can offer some insight into how to decide if a problem is right for you. Particularly valuable for graduate students and postdocs thinking about longer term career paths and the research problems they might want to solve.